Protective Powers: Fullerene C60 and Virgin Olive Oil Shield Against Cadmium-Induced Genotoxicity in Rats
Introduction: Cadmium, a prevalent environmental pollutant, takes various forms such as oxide, chloride, and sulphide, posing significant threats. In this study, we explore the genotoxic impact of fullerene nanoparticles C60 (C60) and virgin olive oil (VOO) on cadmium chloride (CdCl2)-induced genotoxicity in rats.
Study Findings: Surprisingly, both C60 and VOO demonstrated a substantial reduction in genotoxic effects induced by CdCl2, particularly in livers, kidneys, and bone marrow. Chromosomal alterations caused by CdCl2 were reversed by the protective effects of C60 and VOO. Molecular and cytogenetic studies collectively indicate the anti-genotoxic properties of C60 and VOO against CdCl2-induced genotoxicity in rats.
Title: Fullerene-C60 in Squalane: A Clinically Proven Anti-Wrinkle Agent
Introduction: This clinical evaluation delves into the effectiveness of fullerene-C60 dissolved in squalane (LF-SQ cream) for anti-wrinkle cosmetics. The study focuses on wrinkle and skin-surface roughness features, trans-epidermal water loss (TEWL), moisture levels, and visco-elasticity.
Clinical Results: LF-SQ cream significantly enhanced skin moisture and anti-wrinkle formation. Application twice daily proved notably effective after 8 weeks, demonstrating superiority over the placebo without adverse side effects.
Title: Fullerene Nanomaterials: Unveiling Antiallergic Properties
Study Highlights: This research reveals that fullerenes exhibit the capability to inhibit allergic responses in vitro and anaphylaxis in vivo. The study suggests that these molecules might represent a novel approach for controlling diseases influenced by mast cells (MC) and peripheral blood basophils (PBB), such as asthma, arthritis, and autoimmune diseases.
Title: Fullerene-C60/Liposome Complex: Defense Against UVA-Induced Skin Damages
Study Insights: Investigating the defensive effects of a fullerene-C60/liposome complex against UVA-induced damages in skin structure, nucleus, and collagen. The complex significantly repressed UVA-caused corneum scaling, epidermis disruption, breakdown of collagen type I/IV, DNA strand cleavage, and pycnosis/karyorrhexis.
Title: Fullerene as a Therapeutic Reagent for Acne Treatment
Key Findings: Fullerenol, a novel polyhydroxylated fullerene, exhibits inhibitory activity against sebum production and Propionibacterium acnes lipase. This suggests fullerenol’s potential as a beneficial skin care reagent for controlling acne vulgaris by suppressing inflammatory responses and reducing lipase activity.
Title: Fullerene in Skin Care: A Unique Impact on Acne and Skin Regeneration
Research Highlights: Oxidative stress contributes to acne formation, and fullerene’s role as an oxygen radical scavenger inhibits sebum production, suggesting a potential therapeutic role. Fullerene nanoemulsion demonstrates safety and efficacy in protecting collagen from breakdown, presenting cosmeceutical benefits.
Title: Fullerene’s Role in Hair Growth and Scalp Care
Key Results: Fullerene is linked to a 16% increase in hair growth rate after six months, attributed to its protective effects on cells around hair follicles against active oxygen.
Title: Fullerene Nanomaterials Potentiate Hair Growth: A Novel Approach
Study Highlights: Fullerene nanomaterials demonstrate a significant increase in the number of hair follicles, offering a potential solution for conditions leading to hair loss, including alopecia, chemotherapy, and reactions to various chemicals.
Title: Anti-inflammatory Effect of Fullerene C60 in Atopic Dermatitis
Conclusions: The study suggests that fullerene C60 treatment may shift immune responses and restore skin barrier function, offering an alternative treatment for allergic and inflammatory skin conditions.
Title: Fullerene-C60 in Squalane: A Defender Against Skin Cell Injury and Wrinkle Formation
Study Findings: Fullerene-C60 dissolved in squalane demonstrates defensive effects against 2,4-Nonadienal-induced cell injury in human skin keratinocytes (HaCaT) and wrinkle formation in a 3D-human skin tissue model.
